HCID 11194923, compound → HCID 86671522, compound

HRID 2202139Notes

Reaction equation

HRID 2202139 reaction equation
COC([C@]12C(C)(C)[C@H](CC1)CC2=O)=O.[CH3:15][O:16][C:17]([C@@:19]12[C:25]([CH3:27])([CH3:26])[C@@H:22]([CH2:23][CH2:24]1)[CH:21]=[C:20]2[O:28][S:29]([C:32]([F:35])([F:34])[F:33])(=[O:31])=[O:30])=[O:18]>>[CH3:15][O:16][C:17]([C@:19]12[C:25]([CH3:27])([CH3:26])[C@H:22]([CH2:23][CH2:24]1)[CH:21]=[C:20]2[O:28][S:29]([C:32]([F:35])([F:33])[F:34])(=[O:31])=[O:30])=[O:18]

Participants

3

Reactant 2

HCID 11194923HCID 11194923, compoundHCID 86671523HCID 86671523, compound

Product 1

HCID 86671522HCID 86671522, compound

Procedure

The title compound was prepared from 7b by the general procedure described for compound 9a. Brownish oil (68%). 1H NMR (300 MHz, CDCl3) δ ppm 5.81 (d, J=3.74, 1H), 3.77 (s, 3H), 2.51 (dd, J=3.67, 3.67 Hz, 1H), 2.39 (ddd, J=3.71, 8.76, 12.47 Hz, 1H), 2.03-2.13 (m, 1H), 1.65 (ddd, J=3.68, 9.18, 12.65 Hz, 1H), 1.24 (ddd, J=3.72, 9.18, 12.64 Hz, 1H), 1.11 (s, 3H), 0.97 (s, 3H). Exact mass calculated for C12H15F3O5S m/e 328.06. found 328.44.

Sources & evidence

ORD record
ord-cbd6de00e55d424ba1dd14f9910972cf
Source dataset
uspto-grants-2016_06
Patent number
US09365534B2

Reaction notes

Loading…