反应详情

A flask was charged with 4-hydrazinylbenzonitrile hydrochloride (0.70 g, 3.8 mmol.), 4,4-dimethyl-3-oxopentanenitrile (0.48 g, 3.8 mmol) and MeOH and the reaction was heated at refluxed overnight. The reaction was cooled, and the solids which formed upon cooling were filtered off and discarded. Additional solids formed upon further standing (product) along with product material in solution. The solution containing, the solids was concentrated to yield 0.75 g of solid product (92%). MS M+1 (241).

1. temperaturethe reaction was heated
2. temperatureat refluxed overnight
3. temperatureThe reaction was cooled
4. customthe solids which formed
5. temperatureupon cooling
6. filtrationwere filtered off
7. customAdditional solids formed upon further standing (product) along with product material in solution
8. additionThe solution containing
9. concentrationthe solids was concentrated