反应详情

温度

70 °C

A mixture of compound 3 (75 mg, 0.32 mmol) and hydrazine (15 mg, 0.48 mmol) in EtOH (4 mL) was stirred at 70° C. overnight. After the addition of water, the reaction mixture was cooled in an ice bath for 1 hr. The resulting solid was filtered, washed with water, and dried to give compound 4 (50 mg, 72% yield, 100% purity) as a white solid.

1. temperaturethe reaction mixture was cooled in an ice bath for 1 hr
2. filtrationThe resulting solid was filtered
3. washwashed with water
4. customdried