Hydrogen chloride-ethyl acetate → HCID 86728091, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of tert-butyl 4-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxyl propyl)-3-oxopiperazine-1-carboxylate (200 mg, 0.69 mmol) in ethyl acetate (10 mL) was added HCl/ethyl acetate (4 mL). The reaction mixture was stirred at 20° C. overnight, concentrated and used in the next step without further purification. (100 mg, yield 50%) MS (ESI+) e/z: 290.2 [M+1]+.

Provenance & Evidence