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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220265Generated: October 30, 2026

Trifluoroacetic acid → HCID 22376520, compound

https://huagongshe.com/reaction/220265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68412445HCID 68412445—
SolventDichloromethaneHCID 6344—
ProductHCID 22376520HCID 22376520251%

Reaction Steps

To a solution of 800 mg of 3-isoquinolin-4-yl-propionic acid tert.-butyl ester in 6.2 mL of DCM was added 6.2 mL of TFA. The reaction mixture was stirred for 2 h at rt and evaporated to dryness to yield 1.57 g of 3-isoquinolin-4-yl-propionic acid as the trifluoroacetic acid salt as a brown solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202885B2
Source datasetuspto-grants-2012_06
ORD IDord-db9e1456891048f0a1319d995dda2a15
Source noteuspto-grants-2012_06