Hydrochloric Acid → HCID 67462295, 화합물
반응식
C(OC([N:8]1[CH:13]2[CH2:14][CH2:15][CH:9]1[CH2:10][C:11]([OH:22])([C:16]1[N:17]([CH3:21])[CH:18]=[CH:19][N:20]=1)[CH2:12]2)=O)(C)(C)C.[ClH:23]>O1CCOCC1>[ClH:23].[CH3:21][N:17]1[CH:18]=[CH:19][N:20]=[C:16]1[C:11]1([OH:22])[CH2:10][CH:9]2[NH:8][CH:13]([CH2:14][CH2:15]2)[CH2:12]1참가 물질
4
실험 절차
3-Hydroxy-3-(1-methyl-1H-imidazol-2-yl)-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester (0.12 g) was dissolved in a solution of hydrogen chloride in dioxane (4 N, 1.5 mL). The mixture was stirred for 1 hour and the solvent removed by evaporation under vacuum. The solid was triturated from ether to afford the title compound (0.09 g) which was used without further purification.
후처리
- customthe solvent removed by evaporation under vacuum
- customThe solid was triturated from ether
출처 및 근거
- ORD 기록
- ord-8941fc86731c46859a105aa79b1393a3
- 출처 데이터셋
- uspto-grants-2016_06
- 특허 번호
- US09365564B2
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