HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 77231167, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 3-(5-methylpyridin-2-yl)azetidine-1-carboxylate | HCID 71304644 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 77231167 | HCID 77231167 | — |
Reaction Steps
To a solution of 126-2 (37 mg, 0.15 mmol) in DCM (4 mL) was added TFA (1 mL) and the reaction was stirred at room temperature for 2 h. The solvent was removed by rotary evaporation, followed by three cycles of dilution with DCM and evaporation to provide 126-3 that was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365562B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-86c2cbbb3c7c40b1971d866d61c7c384 |
| Source note | uspto-grants-2016_06 |