Formaldehyde → Imidazo[1,2-a]pyridine-3-methanol, 2-cyclopropyl-6-iodo-

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-cyclopropyl-6-iodoimidazo[1,2-a]pyridine (1.5 g) in AcOH (20 ml) were added sodium acetate (2.39 g) and 40% aqueous formaldehyde solution (4 ml), and the mixture was heated at 50° C. for 6 h. The reaction mixture was then cooled to room temperature, and concentrated in vacuo.

Provenance & Evidence