HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2203108Generated: November 2, 2026
ethyl 4-(hydroxymethyl)thiazole-2-carboxylate → HCID 117762896, compound
https://huagongshe.com/reaction/2203108
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | ethyl 4-(hydroxymethyl)thiazole-2-carboxylate | HCID 43558808 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 117762896 | HCID 117762896 | 91.2% |
Reaction Steps
A mixture of ethyl 4-(hydroxymethyl)-1,3-thiazole-2-carboxylate (1.23 g), manganese dioxide (5.71 g) and THF (25 ml) was heated at 50° C. overnight. The inorganic material was removed by filtration, and the filtrate was concentrated in vacuo to give the title compound (1.11 g) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09365540B2 |
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| Source dataset | uspto-grants-2016_06 |
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| ORD ID | ord-13b540fa9a904ad68b560f2fefb8b9a6 |
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| Source note | uspto-grants-2016_06 |
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