HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyl iodide → 5-Fluoro-1-isobutyl-1H-indazole-7-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyl iodide | HCID 10556 | — |
| Reactant | Methyl 5-fluoro-1h-indazole-7-carboxylate | HCID 57425162 | — |
| Product | 5-Fluoro-1-isobutyl-1H-indazole-7-carboxylic acid methyl ester | HCID 118251615 | 41% |
Reaction Steps
Compound 11 was prepared following general method 1, using 5-fluoro-1H-indazole-7-carboxylic acid methyl ester (see WO2011008572, incorporated by reference in its entirety) as starting material and 1-iodo-2-methylpropane as alkylating agent. Yield: 41%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365569B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-eafa903817f4472eaba8444abc744e49 |
| Source note | uspto-grants-2016_06 |