HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 1H-indazole-5-carboxylate → 1-(1-Isobutyl-5-trifluoromethoxy-1H-indazol-7-ylmethyl)-1H-indazole-5-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 1H-indazole-5-carboxylate | HCID 22260640 | — |
| Reactant | (1-Isobutyl-5-trifluoromethoxy-1H-indazole-7-yl)-methanol | HCID 118251620 | — |
| Product | 1-(1-Isobutyl-5-trifluoromethoxy-1H-indazol-7-ylmethyl)-1H-indazole-5-carboxylic acid methyl ester | HCID 118251629 | 46% |
Reaction Steps
Compound 29 was prepared following general method 3A, using compound 21 as a starting material and 1H-indazole-5-carboxylic acid methyl ester as the heterocycle. Yield: 46%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365569B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-420e52b726c8470c8b7d9f0d1747dc8a |
| Source note | uspto-grants-2016_06 |