HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Isobutyl-5-trifluoromethoxy-1H-indazole-7-yl)-methanol → 1-(1-Isobutyl-5-trifluoromethoxy-1H-indazol-7-ylmethyl)-1H-benzoimidazole-5-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Isobutyl-5-trifluoromethoxy-1H-indazole-7-yl)-methanol | HCID 118251620 | — |
| Reactant | HCID 178497374 | HCID 178497374 | — |
| Product | 1-(1-Isobutyl-5-trifluoromethoxy-1H-indazol-7-ylmethyl)-1H-benzoimidazole-5-carboxylic acid methyl ester | HCID 118251577 | 65% |
Reaction Steps
Compound 40 was prepared following general method 3A, using compound 21 as a starting material and 1H-benzoimidazole-5-carboxylic acid methyl ester as the heterocycle. Yield: 65%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365569B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-1ad57aec509143299ffc91eca168c21f |
| Source note | uspto-grants-2016_06 |