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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220430Generated: October 29, 2026

(4-Methoxyphenyl)boronic acid → 2-Chloro-3-(4-methoxyphenyl)pyrazine

https://huagongshe.com/reaction/220430

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Methoxyphenyl)boronic acidHCID 201262—
Reactant2-Chloro-3-(4-chlorophenyl)pyrazineHCID 13199889—
Product2-Chloro-3-(4-methoxyphenyl)pyrazineHCID 1319988854%

Reaction Steps

Use the method used to make 2-chloro-3-(4-chlorophenyl)-pyrazine, using 4-methoxyphenylboronic acid to obtain 2-chloro-3-(4-methoxyphenyl)-pyrazine (54% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202873B2
Source datasetuspto-grants-2012_06
ORD IDord-0d5c38724c0c4658b6308547876c67c1
Source noteuspto-grants-2012_06