HCID 86703200, compound → HCID 86703199, compound

Participants

Reaction Steps

A solution of 4-{2-(2-amino-4-methoxy-pyrimidin-5-yl)-5-[5-chloro-1-(4-methoxy-benzyl)-2-oxo-1,2-dihydro-pyridin-3-yl]-1-isopropyl-4-oxo-1,4,5,6-tetrahydro-pyrrolo[3,4-b]pyrrol-6-yl}-benzonitrile (Step 125.1) (0.137 mmol) in TFA (1 mL) was stirred at 100° C. for 30 min and then the reaction mixture was concentrated. The residue was purified by flash chromatography to afford the title compound as a white solid. ESI-MS: tR=0.75 min, [M+]+516/518 (LC-MS 1).

Provenance & Evidence