HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 68594817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-[2-(4-Fluorophenyl)-pyridin-3-yl]-piperazine-1-carboxylic acid t-butyl ester | HCID 68722827 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68594817 | HCID 68594817 | — |
Reaction Steps
Dissolve 4-[2-(4-fluorophenyl)-pyridin-3-yl]-piperazine-1-carboxylic acid t-butyl ester (0.9 g, 2.52 mmol) in DCM (25 mL). Add trifluoroacetic acid (8.6 g, 5.8 mL, 75.6 mmol). Stir the mixture at room temperature for 2 hr. Purify by a SCX ion-exchange column to give the title preparation. MS (ES): m/z=258 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202873B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-c48641fd662344d69e2693afb2606ef8 |
| Source note | uspto-grants-2012_06 |