Hydrochloric Acid → HCID 66612080, compound

Participants

Reaction Steps

To a solution of phenylmethyl 5-(1-methyl-1H-pyrazol-4-yl)-2-[(phenylmethyl)oxy]-4-(1-piperidinylcarbonyl)benzoate (may be prepared as described in Description 37; 194 mg, 0.38 mmol) in tetrahydrofuran (4 ml) was added lithium hydroxide (33 mg, 1.38 mmol) and water (1 ml). The solution was stirred for 18 hours then 2M hydrochloric acid (0.69 ml, 1.38 mmol) was added and the solvent removed in vacuo to give the title compound as a gum. 170 mg.

Provenance & Evidence