HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2-hydroxy-5-nitrobenzoic acid → 4,5-Diamino-2-hydroxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2-hydroxy-5-nitrobenzoic acid | HCID 21842191 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4,5-Diamino-2-hydroxybenzoic acid | HCID 13158608 | — |
Reaction Steps
Under an H2(g) atmosphere, a suspension of 4-amino-2-hydroxy-5-nitrobenzoic acid (200 mg, 1.01 mmol, 1.00 equiv) and Pd/C (anhydrous) (0.1 g) in HOAc (15 mL) in a 50-mL round-bottom flask was allowed to react, with stirring, overnight at room temperature. The resulting solution was directly taken on to the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09370522B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-c8e11cca5aa645de84043ab848f77ef1 |
| Source note | uspto-grants-2016_06 |