HRID2205187

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID887

Methanol

CH4O

结构：CC(=O)O[C@@H]1[C@H](n2ccc(N)nc2=O)O[C@@](COCc2ccccc2)(C(F)F)[C@H]1OCc1ccccc1

HCID118294215

未命名化合物

PRODUCTS

生成物

结构：Nc1ccn([C@@H]2O[C@@](COCc3ccccc3)(C(F)F)[C@@H](OCc3ccccc3)[C@@H]2O)c(=O)n1

HCID118294393

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID222

Ammonia gas

H3N

PROCEDURE

实验过程

A solution of compound 36 (0.112 g, 0.21 mmol) in NH3.MeOH (4 mL) was stirred at 60° C. for 12 h and then cooled and evaporated to dryness under reduced pressure to give 37 as a white solid. LC-MS: (M+H)+=474.2

WORKUP

后处理

temperaturecooled
customevaporated to dryness under reduced pressure