Ammonium Chloride → HCID 68595789, compound

Participants

Reaction Steps

Prepare the title compound using the methods of Example 135 starting with [3′-(4-fluorophenyl)-2,3,5,6-tetrahydro-[1,2′]bipyrazinyl-4-yl]-(1-isopropyl-1H-pyrazol-4-yl)-methanone (94 mg, 47%). Dissolve the free base (0.087 g, 0.229 mmol) in methanol and add a solution of ammonium chloride (0.012 g, 0.229 mmol) in a minimal volume of methanol. Shake for 18 hr. at room temperature and concentrate to give the title compound (94 mg, 99%). MS (ES): m/z=381 [M+H]+.

Provenance & Evidence