Potassium Hydroxide → HCID 53241517, compound

HRID 2205274Notes

Reaction equation

HRID 2205274 reaction equation
[OH-].[K+].[CH3:3][N:4]([CH3:10])[CH2:5][CH:6]([OH:9])[CH2:7]O.CS([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]/[CH:24]=[CH:25]\[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])(=O)=O>C1(C)C=CC=CC=1>[CH2:16]([O:15][CH:5]([N:4]([CH3:10])[CH3:3])[CH:6]([O:9][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]/[CH:24]=[CH:25]\[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH3:7])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]/[CH:24]=[CH:25]\[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 790783-(Dimethylamino)-1,2-propanediolHCID 59753235Linoleyl methanesulfonate

Product 1

HCID 53241517HCID 53241517, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In a nitrogen atmosphere, dehydrated toluene (30 ml) and potassium hydroxide (1.8 g, 28.8 mmol) were added to a four-necked flask, and 3-(dimethylamino)-1,2-propanediol (0.57 g, 4.78 mmol) was dropped under agitation. Thereafter, linoleyl methane sulfonate (5.0 g, 14.5 mmol) was added, and refluxing was performed at 110° C. for 3 hours. The reaction was terminated because remaining linoleyl methane sulfonate became 4.8% (degree of conversion: 51.1%, integrated value of isomer: 0.142).

Workup

  1. temperaturerefluxing
  2. customThe reaction was terminated

Sources & evidence

ORD record
ord-57cdbe23d6e4476ba94c031819e6d891
Source dataset
uspto-grants-2016_06
Patent number
US09371271B2

Reaction notes

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