Methylhydrazine → HCID 117696427, compound

HRID 2205286Notes

Reaction equation

HRID 2205286 reaction equation
[Br:1][C:2]1[C:3]([CH:8]=O)=[N:4][CH:5]=[CH:6][CH:7]=1.[CH3:10][NH:11][NH2:12]>C(O)C>[Br:1][C:2]1[C:3]([CH:8]=[N:12][NH:11][CH3:10])=[N:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 164142313-Bromopyridine-2-carbaldehyde

Product 1

HCID 117696427HCID 117696427, compoundYield 99.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
80 °C

Procedure

3-bromo-2-formylpyridine (5 g, 26.88 mmol) and methylhydrazine (1.70 mL, 32.25 mmol) are dissolved in ethanol (10 mL) and heated at 80° C. for 2 h. Volatiles are removed under reduced pressure and the residue is re-evaporated several times to give N-[1-(3-Bromo-pyridin-2-yl)-methylidene]-N′-methyl-hydrazine (5.70 g, 99%)

Workup

  1. customVolatiles are removed under reduced pressure
  2. customthe residue is re-evaporated several times

Sources & evidence

ORD record
ord-e2b97b71ee764e5baf9a056f0dbbd852
Source dataset
uspto-grants-2016_06
Patent number
US09371282B2

Reaction notes

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