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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 22053Generated: October 29, 2026

Trifluoroacetic acid → HCID 178440669, compound

https://huagongshe.com/reaction/22053

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178440671HCID 178440671—
SolventChloroformHCID 6212—
ProductHCID 178440669HCID 178440669—

Reaction Steps

To a solution of biphenyl indolizinyl tert-butyl ester (0.039 mmol, the title compound of Example 1926) in 0.5 mL of chloroform is added 0.25 mL of TFA, and the progress of the reaction is monitored by 1H NMR. The resulting solution is stirred at room temperature until the reaction is complete. The mixture is quenched with methanol and concentrated in vacuo. The residue is purified to give the title compound of Example 1927.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05426105
Source datasetuspto-grants-1995_06
ORD IDord-7a69ec3f750544abae4ab67643caedf2
Source noteuspto-grants-1995_06