反应详情

Starting material: N4-(2,4-dichloro-5-methoxyphenyl)-7-methoxyquinazoline-4,6-diamine was prepared according to the same method of preparation of N4-(3-chloro-4-fluorophenyl)-7-(2-methoxy)ethoxyquinazoline-4,6-diamine in WO2008/33747, but the starting material was 4-chloro-7-methoxy-6-nitro-quinazoline and 2,4-dichloro-5-methoxyaniline; other starting materials were prepared as example 1.

1. customother starting materials were prepared as example 1