HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloro-5-methoxyaniline → N4-(2,4-dichloro-5-methoxyphenyl)-7-methoxyquinazoline-4,6-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloro-5-methoxyaniline | HCID 1476636 | — |
| Reactant | 4-Chloro-7-methoxy-6-nitroquinazoline | HCID 10490187 | — |
| Reactant | N4-(3-Chloro-4-fluorophenyl)-7-(2-methoxyethoxy)quinazoline-4,6-diamine | HCID 18765584 | — |
| Product | N4-(2,4-dichloro-5-methoxyphenyl)-7-methoxyquinazoline-4,6-diamine | HCID 86727277 | — |
Reaction Steps
Starting material: N4-(2,4-dichloro-5-methoxyphenyl)-7-methoxyquinazoline-4,6-diamine was prepared according to the same method of preparation of N4-(3-chloro-4-fluorophenyl)-7-(2-methoxy)ethoxyquinazoline-4,6-diamine in WO2008/33747, but the starting material was 4-chloro-7-methoxy-6-nitro-quinazoline and 2,4-dichloro-5-methoxyaniline; other starting materials were prepared as example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371292B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-b8129bda4e6c4c30a9c2f18c1f37816f |
| Source note | uspto-grants-2016_06 |