HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Hydroxyethyl)imidazole → 4-Chloro-3-(3-fluorophenyl)-1-(2-imidazol-1-ylethyl)-5-phenyl-pyrazolo[3,4-c]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Hydroxyethyl)imidazole | HCID 74168 | — |
| Reactant | CID 86717314 | HCID 86717314 | — |
| Product | 4-Chloro-3-(3-fluorophenyl)-1-(2-imidazol-1-ylethyl)-5-phenyl-pyrazolo[3,4-c]pyridazine | HCID 90131804 | — |
Reaction Steps
Compound IIs was synthesized from 4-chloro-3-(3-fluorophenyl)-5-phenyl-1H-pyrazolo[3,4-c]pyridazine and 2-(1H-imidazol-1-yl)ethanol following the general procedure for the Mitsunobu reaction as described above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371332B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-de2f6ea53d074c42b595467d59dca104 |
| Source note | uspto-grants-2016_06 |