HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 137010740, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 137010681 | HCID 137010681 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 137010740 | HCID 137010740 | 151.5% |
Reaction Steps
To a solution of 7-chloro-1-(2,6-difluorophenyl)-3-(4-(morpholin-4-yl)phenyl)-1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-one (100 mg) obtained in Example 161 in ethanol (10 mL) was added 6M hydrochloric acid (0.102 mL) at room temperature, and the reaction mixture was concentrated. The residue was crystallized from ethanol to give the title compound (82 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371320B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-4b1710df7f114295be044f79896f09da |
| Source note | uspto-grants-2016_06 |