HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 59536867, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | tert-Butyl {2-(methylsulphinyl)-1-[2-(trifluoromethyl)phenyl]ethyl}carbamate | HCID 59536884 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 59536867 | HCID 59536867 | — |
Reaction Steps
Of the compound from Example 108A, 400 mg (1.14 mmol), and 567 mg (2.16 mmol) of triphenylphosphine, were dissolved in 14 ml of tetrachloromethane. The reaction mixture was stirred overnight at reflux temperature and then freed from the solvent on a rotary evaporator. The residue was purified by preparative HPLC [Method 20]. The product fraction was freed from the solvent on a rotary evaporator. Drying in an HV gave 340 mg (85% of theory) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202895B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-ebc22034d37a443891cb3c1d656fcdac |
| Source note | uspto-grants-2012_06 |