HRID2206685
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 55 °C
PROCEDURE
实验过程
To a suspension of bromide 29 (1.47 g, 1.59 mmol) in CH3CN (25 mL) were added triphenylphosphine (1.1 g, 3.98 mmol) and CCl4 (2.5 mL) at r.t. The mixture was stirred at 55° C. for 3 hours. The reaction mixture was cooled to r.t and concentrated in vacuo. The residue was purified using normal phase column chromatography to provide the desired product 29-1 (1.03 g, 70%).
WORKUP
后处理
- temperatureThe reaction mixture was cooled
- concentrationconcentrated in vacuo
- customThe residue was purified