Triethylamine → HCID 88919651, compound

Participants

Reaction Steps

1-{2-[3-(3,4,5-Trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-4-(trifluoromethyl)pyrimidin-5-yl}methanamine (0.15 g) and triethylamine (0.051 ml) were dissolved in methylene chloride (3 ml), and to the solution was added cyclopropane carbonyl chloride (0.033 ml, 0.37 mmol) at room temperature. The reaction mixture was stirred overnight and the solvent was distilled off under reduced pressure. The residue was purified by column chromatography to obtain the target compound (0.135 g).

Provenance & Evidence