HCID 86725460, compound → HCID 86725459, compound

Participants

Reaction Steps

To the solution of 4-[5-bromo-2-tert-butyl-6-(2-trifluoromethoxy-ethyl)-pyrimidin-4-yl]-piperazine-1-carboxylic acid benzyl ester (26 mg, 0.048 mmol) in EA (3 mL) was added Pd/C (10.15 mg). Then the mixture was stirred for 40 min under H2 (15 psi) atmosphere. Then the mixture was concentrated and the residue was used in the next step directly.

Provenance & Evidence