反应详情

The title compound 54 is prepared according to the procedure reported in step C of Example 8 with tetralone 53 (1.1 g, 5.09 mmol) and crotonaldehyde (1.43 g, 20.34 mmol) as reactants. Purification by column chromatography on SiO2 (Petroleum/EtOAc=4:1) afford the title compound 54 as an off-white solid. (Yield 0.95 g, 76%).

1. customThe title compound 54 is prepared
2. customPurification by column chromatography on SiO2 (Petroleum/EtOAc=4:1)