HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)benzylamine → 4-[[3-(Trifluoromethyl)phenyl]methylamino]but-3-en-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)benzylamine | HCID 75962 | — |
| Reactant | 3-Buten-2-one, 4-methoxy- | HCID 94297 | — |
| Product | 4-[[3-(Trifluoromethyl)phenyl]methylamino]but-3-en-2-one | HCID 131735883 | — |
Reaction Steps
The title compound 66 is prepared according to the procedure reported in step A of Example 18 with 4-methoxy-3-buten-2-one (0.2 g, 2 mmol) and 3-trifluoromethylbenzylamine (0.35 g, 2 mmol) as reactants. Yellow oil. (Yield 0.48 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-68fe74477521486bb86219ed14a507ae |
| Source note | uspto-grants-2016_06 |