6-Methoxy-alpha-tetralone → HCID 90303965, compound

HRID 2207176Notes

Reaction equation

HRID 2207176 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[C:9](=[O:13])[CH2:8][CH2:7][CH2:6]2.Br[CH2:15][CH2:16][CH:17]=[CH2:18]>>[CH2:18]([CH:8]1[CH2:7][CH2:6][C:5]2[C:10](=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=2)[C:9]1=[O:13])[CH2:17][CH:16]=[CH2:15]

Participants

3

Reactant 2

HCID 141126-Methoxy-alpha-tetraloneHCID 21241Homoallyl bromide

Product 1

HCID 90303965HCID 90303965, compound

Procedure

The title compound 75 is prepared according to the procedure reported in step A of Example 17 with 6-methoxy-1-tetralone (0.88 g, 5.0 mmol) and 4-bromo-but-1-ene (5.0 mmol, 1 equiv) as reactants.

Sources & evidence

ORD record
ord-06f431cb5bc74c62b59801f952f2b3fd
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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