HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Xylyl bromide → 2-[[3-Bromo-1-(m-tolylmethyl)pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Xylyl bromide | HCID 12099 | — |
| Reactant | 2-[(3-Bromo-4-pyridyl)methyl]-6-methoxy-tetralin-1-one | HCID 118558037 | — |
| Product | 2-[[3-Bromo-1-(m-tolylmethyl)pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide | HCID 118558065 | — |
Reaction Steps
The title compound 118 is prepared according to the procedure reported in Example 38.1 with compound 99 (67 mg, 0.2 mmol) and 3-methylbenzyl bromide as reactants. White solid. (Yield 82.5 mg, 56%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-7c52d900cb80467f9aa42fc0cc902209 |
| Source note | uspto-grants-2016_06 |