HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Xylyl bromide → 2-[[3-Acetyl-1-(m-tolylmethyl)pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Xylyl bromide | HCID 12099 | — |
| Reactant | 2-[(3-Acetyl-4-pyridyl)methyl]-6-methoxy-tetralin-1-one | HCID 118558014 | — |
| Product | 2-[[3-Acetyl-1-(m-tolylmethyl)pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide | HCID 118557924 | — |
Reaction Steps
The title compound 120 is prepared according to the procedure reported in Example 38.1 with compound 103 (62 mg, 0.2 mmol) and 3-methylbenzyl bromide (46 μL, 0.34 mmol) as reactants. White solid. (Yield 79.3 mg, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-3f60ed2cffc8467fa0d6f3b16e84223a |
| Source note | uspto-grants-2016_06 |