HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Xylyl bromide → 2-[[3-Acetyl-1-(p-tolylmethyl)pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Xylyl bromide | HCID 7721 | — |
| Reactant | 2-[(3-Acetyl-4-pyridyl)methyl]-6-methoxy-tetralin-1-one | HCID 118558014 | — |
| Product | 2-[[3-Acetyl-1-(p-tolylmethyl)pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide | HCID 118558069 | — |
Reaction Steps
The title compound 130 is prepared according to the procedure reported in Example 38.1 with compound 103 (120 mg, 0.387 mmol) and 4-methylbenzyl bromide (122 mg, 0.66 mmol) as reactants. White solid. (Yield 181.7 mg, 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-d0625fedb9734facadb69c55e985f8c4 |
| Source note | uspto-grants-2016_06 |