Benzyl Bromide → HCID 118558061, compound

HRID 2207223Notes

Reaction equation

HRID 2207223 reaction equation
[F:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH2:8][CH:9]1[CH2:18][CH2:17][C:16]2[C:11](=[CH:12][C:13]([O:21][CH3:22])=[C:14]([O:19][CH3:20])[CH:15]=2)[C:10]1=[O:23].[CH2:24]([Br:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[Br-:31].[CH2:24]([N+:4]1[CH:5]=[CH:6][C:7]([CH2:8][CH:9]2[CH2:18][CH2:17][C:16]3[C:11](=[CH:12][C:13]([O:21][CH3:22])=[C:14]([O:19][CH3:20])[CH:15]=3)[C:10]2=[O:23])=[C:2]([F:1])[CH:3]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 118557954HCID 118557954, compound

Product 1

HCID 118558061HCID 118558061, compound

Procedure

The title compound 133 is prepared according to the procedure reported in Example 38.1 with compound 102 (135.8 mg, 0.43 mmol) and benzyl bromide (87 μL, 0.73 mmol) as reactants. White solid. (Yield 152.1 mg, 72%).

Sources & evidence

ORD record
ord-a4fa609cf49846f5926f23f5ec5fd8aa
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

Loading…