Benzyl Bromide → HCID 118558016, compound

HRID 2207224Notes

Reaction equation

HRID 2207224 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH2:8][CH:9]1[CH2:18][CH2:17][C:16]2[C:11](=[CH:12][C:13]([O:21][CH3:22])=[C:14]([O:19][CH3:20])[CH:15]=2)[C:10]1=[O:23].[CH2:24]([Br:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[Br-:31].[CH2:24]([N+:4]1[CH:5]=[CH:6][C:7]([CH2:8][CH:9]2[CH2:18][CH2:17][C:16]3[C:11](=[CH:12][C:13]([O:21][CH3:22])=[C:14]([O:19][CH3:20])[CH:15]=3)[C:10]2=[O:23])=[C:2]([Cl:1])[CH:3]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 118557804HCID 118557804, compound

Product 1

HCID 118558016HCID 118558016, compound

Procedure

The title compound 134 is prepared according to the procedure reported in Example 38.1 with compound 101 (132.4 mg, 0.4 mmol) and benzyl bromide (95 μL, 2 equiv) as reactants. White solid. (Yield 133.4 mg, 79%).

Sources & evidence

ORD record
ord-c449d56c9aad4cd5aec2dab276479a18
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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