1-Iodopropane → HCID 118557854, compound

HRID 2207225Notes

Reaction equation

HRID 2207225 reaction equation
[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:21][CH3:22])[CH:17]=2)[C:12]1=[O:23])(=[O:3])[CH3:2].[CH2:24]([I:27])[CH2:25][CH3:26]>>[I-:27].[C:1]([C:4]1[CH:5]=[N+:6]([CH2:24][CH2:25][CH3:26])[CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:21][CH3:22])[CH:17]=2)[C:12]1=[O:23])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 336431-IodopropaneHCID 1185580142-[(3-Acetyl-4-pyridyl)methyl]-6-methoxy-tetralin-1-one

Product 1

HCID 118557854HCID 118557854, compound

Procedure

The title compound 135 is prepared according to the procedure reported in Example 38.1 with compound 103 (100.0 mg, 0.323 mmol) and propyl iodide (63 μL, 2 equiv) as reactants. Yellow solid. (Yield 116.2 mg, 75%).

Sources & evidence

ORD record
ord-dff7849526784ca4b49390903b4f1e0d
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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