Benzyl Bromide → HCID 118557824, compound

HRID 2207229Notes

Reaction equation

[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][C:15]([O:22][CH3:23])=[C:16]([O:20][CH3:21])[CH:17]=2)[C:12]1=[O:24])(=[O:3])[CH3:2].[CH2:25]([Br:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[Br-:32].[C:1]([C:4]1[CH:5]=[N+:6]([CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][C:15]([O:22][CH3:23])=[C:16]([O:20][CH3:21])[CH:17]=2)[C:12]1=[O:24])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 90300564HCID 90300564, compound

Product 1

HCID 118557824HCID 118557824, compound

Procedure

The title compound 33 is prepared according to the procedure reported in Example 38.1 with compound 32 (46 mg, 0.14 mmol) and benzyl bromide (34 μL, 0.28 mmol) as reactants. White solid. (Yield 62.3 mg, 91%).

Sources & evidence

ORD record: ord-101324ceee5b4b6e9e54959727f689f9
Source dataset: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09376387B2

Reaction notes

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