Benzyl Bromide → HCID 131735887, compound

HRID 2207233Notes

Reaction equation

[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1/[CH:10]=[C:11]1/[C:12](=[O:24])[C:13]2[C:18]([CH2:19]/1)=[CH:17][C:16]([O:20][CH3:21])=[C:15]([O:22][CH3:23])[CH:14]=2)(=[O:3])[CH3:2].[CH2:25]([Br:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[Br-:32].[C:1]([C:4]1[CH:5]=[N+:6]([CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:7]=[CH:8][C:9]=1/[CH:10]=[C:11]1/[C:12](=[O:24])[C:13]2[C:18]([CH2:19]/1)=[CH:17][C:16]([O:20][CH3:21])=[C:15]([O:22][CH3:23])[CH:14]=2)(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 118557958HCID 118557958, compound

Product 1

HCID 131735887HCID 131735887, compound

Procedure

The title compound 149 is prepared according to the procedure reported in Example 38.1 with compound 97 (83 mg, 0.26 mmol) and benzyl bromide (64 μL, 0.52 mmol) as reactants. White solid. (Yield 101.1 mg, 78%).

Sources & evidence

ORD record: ord-f639f3f6d3ce4fb498d09ab1d0d1e0d7
Source dataset: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09376387B2

Reaction notes

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