Benzyl Bromide → HCID 118558033, compound

HRID 2207234Notes

Reaction equation

HRID 2207234 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[C:8](=[O:14])/[C:7](=[CH:15]/[C:16]1[CH:21]=[CH:20][N:19]=[CH:18][C:17]=1[C:22]([O:24][CH3:25])=[O:23])/[CH2:6]2.[CH2:26]([Br:33])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[Br-:33].[CH2:26]([N+:19]1[CH:20]=[CH:21][C:16](/[CH:15]=[C:7]2/[C:8](=[O:14])[C:9]3[C:5]([CH2:6]/2)=[CH:4][C:3]([O:2][CH3:1])=[C:11]([O:12][CH3:13])[CH:10]=3)=[C:17]([C:22]([O:24][CH3:25])=[O:23])[CH:18]=1)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 118558057HCID 118558057, compound

Product 1

HCID 118558033HCID 118558033, compound

Procedure

The title compound 150 is prepared according to the procedure reported in Example 38.1 with compound 96 (34 mg, 0.10 mmol) and benzyl bromide (25 μL, 0.21 mmol) as reactants. White solid. (Yield 46.1 mg, 90%).

Sources & evidence

ORD record
ord-5f13ec7f4a28456d816f618e163a1ec1
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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