HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyldihydronicotinamide → 2-[(3-acetyl-1-benzyl-4H-pyridin-4-yl)methyl]-6,7-dimethoxy-tetralin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyldihydronicotinamide | HCID 95276 | — |
| Reactant | 2-[(3-Actyl-1-benzyl-pyridin-1-ium-4-yl)methyl]-6,7-dimethoxy-tetralin-1-one bromide | HCID 131735884 | — |
| Product | 2-[(3-acetyl-1-benzyl-4H-pyridin-4-yl)methyl]-6,7-dimethoxy-tetralin-1-one | HCID 118557791 | — |
Reaction Steps
The title compound 162 is prepared according to the procedure reported in Example 39.1 with compound 132 (51 mg, 0.1 mmol) and BNAH (21.4 mg, 1 equiv) as reactants. Yellow solid. (Yield 20.3 mg, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-aa0c71f793ca4b798004eb3298bc6dfa |
| Source note | uspto-grants-2016_06 |