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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2207282Generated: October 31, 2026

Trifluoroacetic acid → HCID 73774718, compound

https://huagongshe.com/reaction/2207282

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 118522197HCID 118522197—
SolventDichloromethaneHCID 6344—
ProductHCID 73774718HCID 7377471835%

Reaction Steps

20 mg (0.03 mmol) of tert-butyl((5-chloro-2-fluoro-4-((6-(2-fluorophenyl)-4-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)oxy)phenyl)sulfonyl)(thiazol-4-yl)carbamate was dissolved in 3 mL of dichloromethane, and 30 uL of trifluoroacetic acid was added thereto, followed by stirring at room temperature for 5 hours. After completion of the reaction as checked by TLC, the solvent was removed to obtain 7.0 mg (35% yield) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09376429B2
Source datasetuspto-grants-2016_06
ORD IDord-3c558e020d9c4b6d825e804c8af2b8c4
Source noteuspto-grants-2016_06