Hydrochloric Acid → HCID 118431715, compound

Participants

Reaction Steps

5-[3-(4-BOC-piperazin-1-yl)-phenyl]-1-(2,4-difluoro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (760.0 mg, 1.6 mmol) prepared in Example 95 was added to a saturated solution of hydrochloric acid in ethyl acetate (10.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 700.0 mg of the titled compound as a brown liquid.

Provenance & Evidence