Hydrochloric Acid → HCID 118431697, compound

Participants

Reaction Steps

5-{3-[4-(N-BOC-amino)-piperidin-1-yl]-phenyl}-1-(2,4-difluoro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (110.0 mg, 6.6 mmol) prepared in Example 98 was added to a saturated solution of hydrochloric acid in ethyl acetate (3.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 100.0 mg of the titled compound as a brown liquid.

Provenance & Evidence