Hydrochloric Acid → HCID 118432029, compound

Participants

Reaction Steps

5-[3-(4-BOC-piperazin-1-yl)-phenyl]-1-(2-chloro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (600.0 mg, 1.1 mmol) prepared in Example 119 was added to a saturated solution of hydrochloric acid in ethyl acetate (5.0 mL). The reaction mixture was stirred at room temperature for 3 hours and then concentrated under reduced pressure to give 610.0 mg of the titled compound as a brown liquid.

Provenance & Evidence