Hydrochloric Acid → HCID 118432053, compound

Participants

Reaction Steps

1-(2,4-Difluoro-phenyl)-5-[2-fluoro-5-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-phenyl]-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (360.0 mg, 0.70 mmol) prepared in Example 147 was added to a saturated solution of hydrochloric acid in ethyl acetate (5.0 mL). The reaction mixture was stirred at room temperature for 3 hours and then concentrated under reduced pressure to give 360.0 mg of the titled compound as a brown liquid.

Provenance & Evidence