Trifluoroacetate → HCID 118432039, compound

Participants

Reaction Steps

1-(2,4-Difluoro-phenyl)-5-[4-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-phenyl]-3-[di-(trifluoromethyl)-hydroxy-methyl]-4,5-dihydro-1H-pyrazole (800.0 mg, 1.32 mmol) prepared in Example 398 and trifluoroacetate (1.0 mL, 13.05 mmol) were added at 0° C. to dichloromethane (6.0 mL). The reaction mixture was stirred at room temperature for 3 hours and then concentrated under reduced pressure to give 800.0 mg of the titled compound as a yellow liquid.

Provenance & Evidence