Hydrochloric Acid → HCID 118431633, compound

Participants

Reaction Steps

1-(2-Chloro-phenyl)-5-[5-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-thiophen-2-yl]-3-[di-(trifluoromethyl)-hydroxy-methyl]-4,5-dihydro-1H-pyrazole (590.0 mg, 0.97 mmol) prepared in Example 416 was added to a saturated solution of hydrochloric acid in ethyl acetate (2.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 590.0 mg of the titled compound as a yellow liquid.

Provenance & Evidence